In addition to hemophilia and von Willebrand disease, there is a group of patients who suffer from rare coagulation disorders; that is, a deficiency or defect in very rare coagulation factors or rare platelet function disorders.
At the Iran Comprehensive Hemophilia Treatment Center, these patients also receive specialized care. Relying on our advanced coagulation laboratory and genetic studies, we provide accurate diagnosis of these diseases and design a treatment plan for each patient tailored to the type and severity of the disorder.
Rare coagulation disorders and factor deficiencies that are investigated and treated at our center
• Fibrinogen (factor 1) deficiency
• Includes congenital afibrinogenia, hypofibrinogenia, and dysfibrinogenia
• Prothrombin (factor 2) deficiency
• Factor 5 deficiency
• Simultaneous deficiency of factor 5 and factor 8
• Factor 7 deficiency
• Factor 10 deficiency
• Factor 11deficiency
• Factor 13 deficiency
• Congenital deficiency of vitamin K-dependent factors
(Combined deficiency of factors 2, 7, 9 and 10)
• Congenital disorders of platelet function
(such as Glanzmann, Bernard-Soulier, and other platelet function disorders)
• Alpha-2 antiplasmin deficiency
Plasminogen activator inhibitor (PAI-1) deficiency
• Plasminogen deficiency
• Other rare and combined deficiencies of the coagulation system
(Based on clinical, laboratory and genetic evaluation of each patient)
Reference Center for Rare Coagulation Disorders
We are one of the few centers in the country that specializes in the diagnosis and treatment of rare coagulation disorders. Regular registration and monitoring of these patients, conducting specialized and genetic tests, and collaborating with scientific centers inside and outside the country have made it possible for patients with rare coagulation factor deficiencies to receive standard and up-to-date treatment.